EASY ACCESS TO OPTICALLY PURE FUNCTIONALIZED GAMMA-ALKYLATED LACTONESSTARTING FROM (2R,3R)-TARTARIC ACID

Authors
FERNANDEZ AM JACOB M GRALAK J ALBAYATI Y PLE G DUHAMEL L
Citation
Am. Fernandez et al., EASY ACCESS TO OPTICALLY PURE FUNCTIONALIZED GAMMA-ALKYLATED LACTONESSTARTING FROM (2R,3R)-TARTARIC ACID, Synlett, (5), 1995, pp. 431-432
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1995
Pages
431 - 432
Database
ISI
SICI code
0936-5214(1995):5<431:EATOPF>2.0.ZU;2-3
Abstract
Protected and deprotected gamma-alkylated dihydroxylactones 8 and 1 ar e prepared from (2R,3R)-tartaric acid. The key step is the highly dias tereoselective reduction of ketones 6 using sodium borohydride in meth anol at low temperature.