MICROWAVE ACCELERATED ORGANIC TRANSFORMATIONS - DIBUTYLSTANNYLENE ACETAL MEDIATED SELECTIVE ACYLATION OF POLYOLS AND AMINO-ALCOHOLS USING CATALYTIC AMOUNTS OF DIBUTYLTIN OXIDE - INFLUENCE OF THE SOLVENT AND THE POWER OUTPUT ON THE SELECTIVITY

The formation of dibutylstannylene acetals from polyols or amino alcoh ols and dibutyltin oxide is accelerated under microwave heating. We ha ve found that under these conditions, only catalytic amounts of dibuty ltin oxide (0.2 mol equiv.) are needed to achieve moderate to excellen t conversions. The method is applied to the selective benzoylation of a variety of polyols and to an amino alcohol. The selectivity of the t ransformation can be modulated upon changes in some experimental varia bles (nature of the solvent and power output of the microwave oven).