ASYMMETRIC-SYNTHESIS OF (-METHYL EPIJASMONATE AND (-)-METHYL CUCURBATE())

Authors
STADTMULLER H KNOCHEL P
Citation
H. Stadtmuller et P. Knochel, ASYMMETRIC-SYNTHESIS OF (-METHYL EPIJASMONATE AND (-)-METHYL CUCURBATE()), Synlett, (5), 1995, pp. 463-464
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1995
Pages
463 - 464
Database
ISI
SICI code
0936-5214(1995):5<463:AO(EA(>2.0.ZU;2-3
Abstract
A short enantio- and diastereoselective synthesis of (+)-methyl epijas monate 1 and (-)-methyl curcurbate 2, two essential components of jasm in oil is described. The key step is a nickel catalyzed ring closure, which sets up three chiral centers with high diastereoselectivity.