TREATMENT OF LEGIONELLA-PNEUMOPHILA LUNG ABSCESS WITH CLINDAMYCIN

Authors
BUGGY BP SARAVOLATZ LD
Citation
Bp. Buggy et Ld. Saravolatz, TREATMENT OF LEGIONELLA-PNEUMOPHILA LUNG ABSCESS WITH CLINDAMYCIN, Clinical infectious diseases, 20(5), 1995, pp. 1158-1162
Citations number
33
Categorie Soggetti
Microbiology,Immunology,"Infectious Diseases
Journal title
Clinical infectious diseases → ACNP
ISSN journal
10584838
Volume
20
Issue
5
Year of publication
1995
Pages
1158 - 1162
Database
ISI
SICI code
1058-4838(1995)20:5<1158:TOLLAW>2.0.ZU;2-A
Abstract
Clindamycin was used to successfully treat a lung abscess caused by Le gionella pneumaphila. The activity of clindamycin, erythromycin, and r ifampin against cell-associated growth of L. pneumophila in human mono cytes was determined by broth time-kill methodology. More killing of c ell-associated growth of L. pneumophila was achieved with clindamycin than with erythromycin. Synergy with rifampin was demonstrated with bo th erythromycin and clindamycin.