PERIODIC ANGIOEDEMA WITH EOSINOPHILIA - INCREASED SERUM LEVEL OF INTERLEUKIN-5

Authors
OKUBO Y SATO E HOSSAIN M OTA T YOSHIKAWA S SEKIGUCHI M
Citation
Y. Okubo et al., PERIODIC ANGIOEDEMA WITH EOSINOPHILIA - INCREASED SERUM LEVEL OF INTERLEUKIN-5, Internal medicine, 34(2), 1995, pp. 108-111
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
Internal medicine → ACNP
ISSN journal
09182918
Volume
34
Issue
2
Year of publication
1995
Pages
108 - 111
Database
ISI
SICI code
0918-2918(1995)34:2<108:PAWE-I>2.0.ZU;2-P
Abstract
A 48-year-old man developed episodic non pitting edema and eosinophili a. Symptoms were alleviated promptly when treated with prednisolone. H owever, major basic protein (MBP), eosinophil cationic protein (ECP), and eosinophil-derived neurotoxin (EDN) levels in the serum as well as the total number of eosinophils remained high. During periods of atta ck serum levels of interleukin-5 (IL-5) were elevated, but the levels were lowered following treatment, suggesting that IL-5 is involved in periodic angioedema with eosinophilia.