Firm myocardium in cardiopulmonary resuscitation (CPR) is a rarely des
cribed yet potentially important condition. To investigate the clinica
l nature and implications of firm myocardium in CPR, we retrospectivel
y analyzed 59 adult patients with nontraumatic out-of-hospital cardiac
arrest who underwent open-chest CPR in the emergency department and h
ad heart consistency recorded. Consistency of the myocardium varied co
nsiderably between patients. Firm myocardium was noticed in 36 cases,
mainly in the left ventricle (firm myocardium group). The remaining 23
hearts were not firm (soft myocardium group). Some hearts had an incr
ease in their consistency during CPR. Patient characteristics were sim
ilar in the two groups. The firm myocardium group showed greater base
deficit on arterial blood gas analysis, suggesting more severe ischemi
c injury. Very firm heart had a close association with an extremely lo
w end-tidal CO, tension. Histopathological examination revealed hypert
rophy and fibrosis common to the two groups. Both groups received simi
lar treatment except for a shorter duration of direct cardiac massage
in the firm myocardium group, although a reasonably prolonged effort w
as made in most cases. The firm myocardium group responded poorly to t
reatment. Very firm myocardium never contracted, whereas less firm myo
cardium usually showed some, albeit insufficient, activity. Most cases
in the soft myocardium group regained a pulse. Our results suggest th
at firm myocardium: (1) is common in patients who receive CPR in the e
mergency department, (2) indicates ischemic contracture, (3) is not un
iform in firmness, reflecting the degree of ischemia and (4) is a grav
e prognostic factor in cardiac resuscitation. Copyright (C) 1996 Elsev
ier Science Ireland Ltd