Growth hormone (GH) cDNA has been isolated by polymerase chain reactio
n (PCR) from cDNA library prepared from pituitary gland of Baikal omul
(Coregonus autumnalis Pallas). The cDNA was found to encode a polypep
tide of 210 amino acids, including a signal of 22 amino acids. Compara
tive analysis showed high nucleotide-sequence homology between the omu
l growth hormone and those of other Salmoniformes species.