H. Sato et al., VASORELAXANT ACTIVITY OF UOROALKYL-6-NITRO-2H-1-BENZOPYRAN-4-CARBOTHIOAMIDE AND -FLUOROALKYL-6-NITRO-2H-1-BENZOPYRAN-4-CARBOXAMIDE K+ CHANNEL OPENERS, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 233-236
Synthesis and vasorelaxant activity of oroalkyl-6-nitro-2H-1-benzopyra
n-4-carbothioamides 4 and 6 and -carboxamides 5 and 7 are described. P
otent smooth muscle relaxant activity was displayed by 6c.