Nj. Carruthers et al., SYNTHESIS AND RESOLUTION OF BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFINIC ACID A POTENT GABA(B) RECEPTOR-LIGAND, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 237-240
The synthesis and resolution of beta-(Aminomethyl)-4-chlorobenzeneetha
nesulfinic acid together with the GABA(B) receptor affinity for the ra
cemate and enantiomers is described. In addition the synthesis and GAB
A(B) receptor affinity of the enantiomers of the known GABA(B) antagon
ist (Saclofen) is reported for the first time