The indications and outcome of the wear of gas-permeable (GP) scleral
contact lenses in 118 eyes of 85 patients attending a Scleral Contact
Lens Clinic during a 5-year period from July 1988 to June 1993 were an
alysed. Ninety-nine eyes (83.9%) were originally fitted with PMMA lens
es and were subsequently changed to GP lenses, whereas 19 (16.1%) were
fitted with GP lenses from the outset. The mean duration of GP sclera
l lens wear was 15.3 months, with a range between 3 and 58 months. The
indications for refitting the cases previously wearing PMMA scleral l
enses with GP material were related to problems of chronic hypoxia. Th
irty-three eyes (26.8%) had previous episodes of corneal oedema, and o
f the 27 that had a minimum of 3 months' follow-up, none experienced f
urther episodes of oedema. Of the 32 eyes (26%) that had developed cor
neal vascularisation associated with PMMA scleral lens wear, two eyes
were noted to have significant vessel regression after a period of GP
wear, whereas in the remainder of cases, vessels remained static and n
onprogressive. Thirty additional eyes (24.2%) experienced inadequate w
ear times associated with discomfort, and in these eyes the change to
GP scleral lenses produced a statistically significant reduction in th
e inability to wear lenses beyond 4 h (p < 0.05).