RENAL AND HEPATIC ANGIOMYOLIPOMAS IN A CHILD WITHOUT EVIDENCE OF TUBEROUS SCLEROSIS

A renal neoplasia, displaying the typical features of angiomyolipoma ( an admixture of smooth muscle cells, mature adipocytes and tangles of thick-walled blood vessels) was found in a nine-year-old boy. In addit ion, cytoplasmic crystalloid structures and HMB 45 positivity were fou nd in smooth muscle cells. Similar findings were also observed in a sm all nodule of the liver. According to literature data, angiomyolipoma is very rare in children and almost exclusively associated with tubero us sclerosis. Our case suggest that the diagnostic hypothesis of angio myolipoma can not be disregarded when a renal mass is identified in a young patient even in a clinical setting other than tuberous sclerosis .