Health hazards related to activities performed in pathology department
s have represented, in recent years, an increasing concern among patho
logists and pathology technicians. The major occupational health probl
ems encountered in pathology departments are reviewed. They include bi
ological hazards (tuberculosis, hepatitis, HIV other infectious diseas
es), chemical hazards (formaldehyde, xylene(s), aromatic amines, metha
crylates, glutaraldehyde, latex) and physical hazards (cut injuries, a
ccidental fires, radiation). Current data suggest that infections (par
ticularly, tuberculosis and hepatitis) still represent the more releva
nt risk. Exposure to HIV and Creutzfeldt-Jakob agent may be highly har
mful but containment measures have been proven to be effective. The ac
tual adverse effects due to chemicals seem to be less alarming than wa
s previously believed. Attaining a safe work environment is an inheren
t element of good quality assurance management. This task is largely a
matter of information, education, organization and common sense. Well
-designed premises, efficient equipment and well-trained personnel are
the keys to preventing and minimizing hazardous exposures. In order t
o provide current information that may be used by pathology staff to i
mplement the functional quality of the workplace, organizational and p
reventive measures are described.