The regional cerebral blood flow correlates of the active fixation of
an imagined target were studied in five healthy humans using the posit
ron emission tomography activation paradigm. The fixation task was con
trasted to a passive control condition, both tasks being performed in
total darkness. Blood flow increases were observed in the frontal eye
fields and supplementary eye fields and in the median cingulate gyrus.
We suggest that the network of these activated regions mediates the i
nteractions between ocular fixation, eye movements and directed visual
attention.