K. Mikkola et al., LONG-TERM RESULTS OF RESTORATIVE PROCTOCOLECTOMY FOR ULCERATIVE-COLITIS, International journal of colorectal disease, 10(1), 1995, pp. 10-14
To study the long-term effects of restorative proctocolectomy with J-p
ouch for ulcerative colitis 100 consecutive patients were examined a m
ean of 5.6 years after ileal pouch-anal anastomosis (IPAA). Seventy-th
ree percent of patients were on steroids and 22% had a preceding sever
e attack of colitis before IPAA. The overall early and late complicati
on rates were 40% and 33%, respectively. Failure rate was 5% and all f
ailures requiring pouch excision occurred within the first three posto
perative years. Pouchitis (36%) was the commonest late complication. A
preceding severe attack of colitis was an important prognostic sign o
f late anastomotic complications, troublesome incontinence and ultimat
e failure. The daily mean stool frequency varied from 4.5 to 6.9. Afte
r a short learning period continence - stabilised and minor incontinen
ce was common (57%). The majority of patients (72%) were either very s
atisfied or had no problems in daily activities after IPAA. Ten patien
ts were dissatisfied after surgery due to obvious medical reasons in m
ost of them.