The recent successful immunization of experimental animals using nucle
ic acids has provided a revolutionary new approach in vaccinology, in
this article, Gory Waine and Don McManus examine the potential of nucl
eic acid vaccines for their effectiveness not only against infectious
and parasitic organisms exhibiting on intracellular Phase during their
life cycle, but also against parasitic helminths, whose life cycle st
ages are either predominantly or completely extracellular.