Objective: To determine whether the symptoms of endometriosis were rel
ated to the number and/or location of endometrial implants and the num
ber and/or location of adhesions. Design: Prospective, double-blind st
udy. Patients: Seventy consecutive female surgical patients undergoing
diagnostic and operative laparoscopy for pain, infertility, or both.
Interventions: Patients completed a self-administered questionnaire on
e day before laparoscopy. Main Outcome Measures: The number, type, and
location of endometrial implants and the number, type, and location o
f adhesions were evaluated during laparoscopy. These were compared wit
h the type and severity of endometriosis symptoms as reported by patie
nts. Results: The total number of ectopic endometrial implants was ass
ociated directly with the intensity of dysmenorrhea experienced by pat
ients in the 60 days before operative laparoscopy (n = 47). Patients w
ith low pain scores had significantly fewer implants than patients wit
h high pain scores. Conclusions: The intensity of menstrual pain is re
lated to the number of endometrial implants in patients with endometri
osis.