Pl. Peterson, THE TREATMENT OF MITOCHONDRIAL MYOPATHIES AND ENCEPHALOMYOPATHIES, Biochimica et biophysica acta. Molecular basis of disease, 1271(1), 1995, pp. 275-280
This paper briefly summarizes the results of a long-term, open pharmac
otherapy trial in 16 patients with well-characterized mitochondrial di
sease. Outcome measures included repeated clinical evaluation, P-31-NM
R spectroscopy and near-infrared spectroscopy. Treated patients appear
ed to survive longer with less functional disability and medical compl
ications than typically seen in clinical practice.