ANALYSIS OF COUMARINS BY MICRO-HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHYMASS-SPECTROMETRY WITH A PARTICLE-BEAM INTERFACE

Authors
CAPPIELLO A FAMIGLINI G MANGANI F TIRILLINI B
Citation
A. Cappiello et al., ANALYSIS OF COUMARINS BY MICRO-HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHYMASS-SPECTROMETRY WITH A PARTICLE-BEAM INTERFACE, Journal of the American Society for Mass Spectrometry, 6(2), 1995, pp. 132-139
Citations number
35
Categorie Soggetti
Chemistry Physical","Chemistry Analytical",Spectroscopy
Journal title
Journal of the American Society for Mass Spectrometry → ACNP
ISSN journal
10440305
Volume
6
Issue
2
Year of publication
1995
Pages
132 - 139
Database
ISI
SICI code
1044-0305(1995)6:2<132:AOCBML>2.0.ZU;2-7
Abstract
Coumarins are a large group of compounds that are naturally present in plant tissues and that exhibit a wide range of pharmacological proper ties. Analytical methods based on chromatographic techniques and conve ntional detectors are inadequate to accurately analyze coumarins in co mplex matrices such as plant extracts. In this article a new method ba sed on a modified particle beam liquid chromatography-mass spectrometr y interface is described. The method allows specific and accurate dete rmination of several coumarins in biological matrices. An application regarding the analysis of 18 coumarins in the extract of Smyrnium perf oliatum L. is also reported.