Background: Cystic duct leak is a rare complication of laparoscopic su
rgery. To study the incidence, presentation, and management of cystic
duct leak (CDL) after laparoscopic cholecystectomy (LC) a retrospectiv
e study of centers doing large numbers of LC was done. Methods: Patien
t information was obtained by a questionnaire sent to experienced lapa
roscopic surgeons. This queried demographic information, course of the
original operation, presentation, diagnostic studies, and management
of CDL after LC. Results: Some 22,165 LCs were performed by 24 surgeon
s; there were 58 cases of CDL (0.26%); 21% of the surgeons reported no
CDLs; 60% of CDLs occurred in the first 25% of each surgeon's experie
nce, but CDLs continue to occur even in their most recent 10% of cases
. Preoperative symptoms, prior surgery, and comorbid conditions did no
t predict CDL. Acute cholecystitis was present at initial surgery in 4
7%. Symptoms of CDL an average of 3.1 days post-LC were abdominal pain
78%, fever 26%, nausea 35%, vomiting 22%, abdominal distention 26%, a
nd shoulder pain 12%. WBCs and LFTs were elevated in more than two-thi
rds of the cases. ERCP was most frequently used to diagnose CDL (53%)
and was successful in 97%, although sonogram (40%) and HIDA scan (26%)
and CT (26%) were also used. Management included ERCP and ductal deco
mpression in 27 patients, percutaneous drainage in 13 pa patients, ope
n laparotomy in 14, laparoscopy in three, and observation in two. Pati
ents were discharged an average of 7.4 days post discovery of leak. St
ents were removed an average of 30 days post ERCP. Ninety-four percent
were complete cures. There was one post-treatment abscess. Two deaths
due to multisystem failure unrelated to leak occurred. Conclusions: C
ystic duct leak is rare and fairly easily diagnosed. It occurs more fr
equently during the learning curve, but also after much experience. ER
CP and ductal decompression play a large role in treatment, but almost
all standard methods of treatment yield successful outcomes with low
morbidity.