Background: An effort was made to assess the feasibility, safety, and
outcome of laparoscopic procedures performed in patients with Crohn's
disease. Methods: A prospectively maintained laparoscopic database was
analyzed regarding operation time, intra- and postoperative complicat
ions, conversion to laparotomy, and length of hospitalization. Fifty-o
ne patients (23 males and 28 females) with a mean age of 36 (20-79) ye
ars underwent a laparoscopic or laparoscopic-assisted procedure for Cr
ohn's disease. The indications included terminal ileitis in 31 patient
s, colitis in 11, perianal disease in four, duodenal Crohn's disease i
n three, and rectovaginal and rectourethral fistula in one patient eac
h. Thirty-two patients underwent an ileocolic resection; total abdomin
al colectomy with ileorectal anastomosis was performed in six patients
with end ileostomy in one, take down of end ileostomy and ileorectal
anastomosis in three, duodenal bypass gastrojejunostomy in three, and
loop ileostomy in six patients. Results: The mean operating time was 2
.4 (0.6-4.5) h and the mean length of hospital stay was 5.1 (3-18) day
s. Eight complications were noted in seven patients (14%), which inclu
ded enterotomy in two patients, bleeding in two, stoma obstruction in
two, pelvic sepsis in one, and efferent limb obstruction in one. The p
rocedure was converted to laparotomy in seven patients (14%) due to a
large inflammatory mass in five and to bleeding in two patients; there
was no mortality. Conclusion: Laparoscopic surgery is a feasible, ver
satile, and safe modality in the surgical management of Crohn's diseas
e. Despite the often-malnourished state of these steroid-dependent pat
ients with intraabdominal inflammatory conditions, morbidity, procedur
al length, and length-of-hospitalization data are all similar to resul
ts previously reported for less-challenging laparoscopic colorectal pr
ocedures.