APPROACH TO THE CONFORMATIONAL BEHAVIOR OF TETRAAZAMACROCYCLES IN THESOLUTION-STATE - NMR AND MOLECULAR MODELING STUDIES

Authors
BOETZEL R FAILLA S FINOCCHIARO P HAGELE G
Citation
R. Boetzel et al., APPROACH TO THE CONFORMATIONAL BEHAVIOR OF TETRAAZAMACROCYCLES IN THESOLUTION-STATE - NMR AND MOLECULAR MODELING STUDIES, Magnetic resonance in chemistry, 33(2), 1995, pp. 128-133
Citations number
35
Categorie Soggetti
Spectroscopy,Chemistry
Journal title
Magnetic resonance in chemistry → ACNP
ISSN journal
07491581
Volume
33
Issue
2
Year of publication
1995
Pages
128 - 133
Database
ISI
SICI code
0749-1581(1995)33:2<128:ATTCBO>2.0.ZU;2-O
Abstract
The differences in complexation behaviour of two diastereomeric tetraa zamacrocycles, meso (1) and racemic (2) 2,14-hexamethyl-1,4,8,11-tetra azacyclotetradecane, are explained by different conformations in solut ion, 1 being one stable conformer of almost rigid structure while 2 sh ows higher conformational flexibility to avoid steric strain, The meth ods used were H-1 and C-13 NMR and molecular modelling.