The clinical picture of lead neuropathy was classically described as a
painless progressive motor neuropathy with axonal loss, The literatur
e review fails to demonstrate a consensus on the site of axonal loss.
This is an EMG report of a patient who developed a late lead neuropath
y after a shotgun injury, A 69-year-old Filipino, healthy, male nondri
nker sustained a shotgun injury to his left elbow, Nineteen years late
r he developed abdominal pain, followed by generalized weakness, dista
l greater than proximal in the extremities, and impaired pin-prick, pr
oprioception, and two-point discrimination. He became nonambulatory an
d totally dependent in daily activities, He was lost to follow-up for
2 years until January 1993 when he presented with a blood lead level o
f 84 mu g/dL. EMG examination revealed a sensorimotor peripheral polyn
europathy with severe axonal loss. This case demonstrates that axonal
loss is the predominant feature in lead neuropathy and the location of
pathology is in the peripheral nerves. (C) 1995 John Wiley & Sons, In
c.