Fat grafting to the penis has recently become popular in some parts of
the country. Surgery is commonly performed in the office, where peer
review is lacking or nonexistent. A single case is reported documentin
g a poor cosmetic and functional result after irregular resorption of
grafted fat. The external appearance of the penis remained stable for
months, even though later biopsy revealed all the grafted fat to be de
ad. Analogy with pseudolipoma of Glisson's capsule is provided, showin
g that dead fat cells can survive for years or even a lifetime without
absorption by the body. Several complications are examined in this ar
ticle, and other potential risks are also discussed. The operation, al
though technically easy to perform, has many serious potential side ef
fects that should be understood.