TREATMENT OF NEVUS OF OTA WITH AUTOLOGOUS-CULTURED EPITHELIUM GRAFTING COMBINED WITH DERMABRASION

Nevus of Ota is an anomaly of the dermal melanocytes, which lies prima rily in the deep dermis. It causes discoloration of the face and induc es a remarkable disfigurement to the patients, This report demonstrate s the favorable results of 3 male patients treated with autologous-cul tured epithelium grafting combined with dermabrasion. The lesions on t he cheek, forehead, and temple were dermabraded to the deep dermal lay er. The cultured epithelium obtained from preauricular skin or medial upper arm were grafted on the wounds. The grafts took well, and most o f the grafted site healed after 1 week. Facial appearances improved re markably. There was minimal scar formation and minimal recurrence of n evus cell. After long-term follow-up, the grafted sites resembled the adjacent normal face skin in terms of appearance and texture.