AN ASSOCIATION BETWEEN RECURRENT ORO-GENITAL ULCERATION AND NONSTEROIDAL ANTIINFLAMMATORY DRUGS

Recurrent ore-genital ulceration is a common condition of unknown aeti ology. This paper describes a patient who had severe recurrent ore-gen ital ulceration which was unresponsive to conventional therapy. The pa tient was taking nonsteroidal anti-inflammatory drugs (NSAIDs) prescri bed for osteoarthritis. When she stopped this medication, she had no f urther genital ulceration and the pattern of her oral ulceration was d ramatically improved. There have been no previously reported cases of recurrent ore-genital ulceration associated with NSAIDs.