There have been many reports of the inadvertent removal of an ectopic
thyroid gland that was mistaken for a thyroglossal duct cyst. The diff
erentiation of these two conditions is extremely important, because in
advertent removal of an ectopic thyroid gland may result in profound h
ypothyroidism. The authors report the case of a 5-year-old girl with a
n ectopic thyroid gland in whom the preliminary diagnosis was a thyrog
lossal duct cyst. They review the embryologic features in the developm
ent of an ectopic thyroid gland and discuss an approach to the managem
ent of this congenital anomaly.