Spinal tuberculosis, the most common form of skeletal involvement, is
increasing in prevalence because of the resurgence of tuberculosis dur
ing the past decade in patients with AIDS, the spread of tuberculosis
among the homeless, and the expanding immigrant population. Spinal inf
ection is usually the result of hematogenous seeding of the vertebral
body, and the diagnosis often remains elusive because of the indolent
nature of tuberculous infection, As a result, the radiographic finding
s and the signs and symptoms are typically far advanced when the diagn
osis is finally established. Radiographic manifestations of tuberculou
s spondylitis include intraosseous and paraspinal abscess formation, s
ubligamentous spread of infection, vertebral body destruction and coll
apse, and extension into the spinal epidural space. Significant instab
ility and deformity of the spine can result, mandating prompt diagnosi
s and treatment to prevent permanent neurologic damage. The purpose of
this essay is to illustrate the broad spectrum of imaging findings on
plain radiographs, bone scans, CT scans, myelograms, and MR images of
patients with spinal tuberculosis. The value of MR imaging in determi
ning the extent of disease is demonstrated.