Vulval pain and pruritus are symptoms associated with benign or malign
ant diseases. The paucity of information regarding aetiological factor
s confounds a logical approach to successful therapeutic and preventat
ive strategies. Research continues to address the possible relationshi
p between human papillomavirus and benign, premalignant and malignant
vulval conditions. Although present in many conditions, oncogenesis ca
used by human papillomavirus has yet to be proven as a cause of vulvar
premalignant and malignant diseases. The natural history and manageme
nt of these and benign disorders have been reported during the period
of review. Some of the new findings may alter present concepts and pra
ctices.