LACK OF CORRELATION BETWEEN CADMIUM IN SEMINAL PLASMA AND FERTILITY STATUS OF NONEXPOSED INDIVIDUALS AND 2 CADMIUM-EXPOSED PATIENTS

Cadmium concentrations were determined in semen samples of 12 men with proven fertility (group I) and 44 normozoospermic patients (group II) as well as 118 unselected patients of an infertility clinic (group II I) and 2 industrial workers with occupational exposure to cadmium, Mea n cadmium concentrations in seminal plasma for groups I, II, and III d id not show significant differences: 0.38 +/- 0.64; 0.43 +/- 0.69; 0.4 4 +/- 0.73 (mean +/- SD, mu g/L), but the two cadmium-exposed patients revealed exceptionally high cadmium levels: 3.46 mu g/L and 2.99 mu g /L, respectively, There was no significant correlation between seminal cadmium concentrations and conventional semen parameters or between c admium concentration and the fertility status of the patients, However , mean cadmium concentrations in seminal plasma of normozoospermic pat ients were higher in the group of smokers (0.55 +/- 0.81 mu g/L), comp ared with the group of nonsmokers (0.42 +/- 0.67 mu g/L), and there wa s a weak correlation between cadmium concentration and number of cigar ettes consumed per day.