Iv. Osechinsky et al., DESCRIPTIVE ANALYSIS OF THE EXCESS OF ACU TE-LEUKEMIA INCIDENCE AMONGCHILDREN LIVING IN BRYANSK TERRITORY, Gematologia i transfuziologia, 39(5), 1994, pp. 7-11
12 cases of ALL, 2 cases of ANLL and 3 cases of NHL have been register
ed among children aged 0-15 living in 6 Bryansk territory regions expo
sed to radionuclide contamination after the Chernobyl accident. The st
udy covers the period from 1986 to 1991. There was an excess of acute
Leukemia incidence in 1986 as indicated by 7 ALL and 1 ANLL cases. For
ALL relative risk was 4.49, p = 0.006. In 2 cases AL was diagnosed be
fore the accident, 2 patients fell ill in June, 2 in July, 1 in August
, we have no exact date for 1 patient. Relative risk has never exceede
d 1.0 for all the analyzed hemoblastoses within the last 5 years. The
Poisson probability of chance occurrence of 8 AL cases in supervision
regions during one year is 0.0004. Sex distribution of the cases was a
typical either: 7 from 8 patients were boys. Binomial probability is 0
.056 under the standard sex ratio 6:5. No evidence was obtained that t
his high incidence of childhood leukemia extends to neighbour regions
of the Gomel, Mogilev and Bryansk territories. The descriptive epidemi
ological analysis has confirmed the existence of childhood leukemia in
cidence excess in 1986, but failed to explain its cause. Analysis of i
ncidence rates alone is not enough to confirm connection between leuke
mia hazard and Chernobyl accident.