Isometric force tracking and force aiming modified by visual feed-back
was investigated in Parkinsonian (PD) and control subjects. Productio
n and maintenance of isometric force, production and release of isoton
ic force, and maximum force were tested. Statistical analysis revealed
that the PD patients could perform most force tasks in a similar mann
er to that of control subjects. However, PD patients had difficulties
in sustaining target force over a 30-s period and in performing rapid
alternating movements. The major finding in PD patients was an inabili
ty to precisely release a target force. Overall these data suggest tha
t the release of a produced force is a sensitive motor control paramet
er in Parkinson's disease.