Using the population based data resources of the Rochester Epidemiolog
y Project and a postal survey, we estimated all costs (direct medical,
indirect medical, and nonmedical) incurred among a population based p
revalence cohort of individuals with osteoarthritis (OA) and a nonarth
ritic comparison cohort, Cost estimates were compared between the 2 gr
oups adjusting for age and sex differences. Our results demonstrated t
hat people with OA incur substantial incremental medical costs, not on
ly for arthritis care, but also for the care of neurological, gastroin
testinal, cardiac, and respiratory conditions compared to nonarthritic
s. These data also demonstrated important and statistically significan
tly higher levels of work disability among people with OA compared to
their age and sex adjusted peers without arthritis from the same commu
nity.