SEQUENCE-ANALYSIS AND EXCLUSION OF PHOSDUCIN AS THE GENE FOR THE RECESSIVE RETINAL DEGENERATION OF THE ABYSSINIAN CAT

Authors
GORIN MB TO AC NARFSTROM K
Citation
Mb. Gorin et al., SEQUENCE-ANALYSIS AND EXCLUSION OF PHOSDUCIN AS THE GENE FOR THE RECESSIVE RETINAL DEGENERATION OF THE ABYSSINIAN CAT, Biochimica et biophysica acta, N. Gene structure and expression, 1260(3), 1995, pp. 323-327
Citations number
20
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1260
Issue
3
Year of publication
1995
Pages
323 - 327
Database
ISI
SICI code
0167-4781(1995)1260:3<323:SAEOPA>2.0.ZU;2-Z
Abstract
Phosducin was evaluated as a candidate gene for the recessive retinal degeneration in the Abyssinan cat, rdAc, using reverse transcription a nd polymerase chain amplification. The nucleotide sequence of the cat phosducin coding region was determined except for 23 bp at the 5' end. Single-strand conformation analysis of a silent polymorphism within t he coding region established the nonlinkage of the phosducin gene with the rdAc locus.