Liver biopsies help define the disease process and can assist the clin
ician in forming a prognosis. The small size of Liver biopsy specimens
and limited responses of the liver to a wide spectrum of injuries oft
en do not allow for a specific etiologic diagnosis. Determination of t
he distribution and morphology of the lesion often provides useful dia
gnostic and prognostic information. Maximum value can be attained from
Liver biopsies when the histologic findings are correlated with the r
esults of other diagnostic tests and there is good communication betwe
en the clinician and pathologist.