ALDOL REACTIONS OF GAMMA-METHYLENE AND EPSILON-METHYLENE IN 5-MEMBERED HETEROAROMATIC-COMPOUNDS

Authors
LEE CK GONG JS LEE ISH
Citation
Ck. Lee et al., ALDOL REACTIONS OF GAMMA-METHYLENE AND EPSILON-METHYLENE IN 5-MEMBERED HETEROAROMATIC-COMPOUNDS, Journal of heterocyclic chemistry, 32(1), 1995, pp. 239-242
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
32
Issue
1
Year of publication
1995
Pages
239 - 242
Database
ISI
SICI code
0022-152X(1995)32:1<239:AROGAE>2.0.ZU;2-7
Abstract
5-Methyl-2-thiophenecarboxaldehyde (1a) and 3-methyl-2-thiophenecarbox aldehyde (6) underwent intermolecular aldol reactions in which the met hyl group behaved as active methylene in the presence of potassium cya nide. 5-Methylfurfural (1b) gave only 5,5'-dimethylfuroin in the prese nce of potassium cyanide. But 1b formed an intermolecular aldol reacti on product when sodium hydroxide was used.