T. Lebret et al., USE OF A DIGESTIVE MUCOSAL GRAFT IN URETHROPLASTY - AN EXPERIMENTAL-STUDY - PROSPECTIVE UTILIZATION OF THE APPENDIX MUCOSA, European urology, 27(1), 1995, pp. 58-61
Colic mucosa was used as a graft for urethral construction in 9 Spragu
e-Dawley rats. A urethrectomy was performed in each rat and then a ure
throplasty built with the colic mucosa taken from a segmental colectom
y. After 6 weeks to 3 months, all of these rats developed a typical ur
othelium. The digestive mucosa has been transformed into urothelium or
acts as a stent to guide regrowth from each end. These results are en
couraging, but the use of the appendix mucosa for hypospadias repair a
nd for urethroplasty deserves further study.