HIGHLY DIASTEREOSELECTIVE BIS-HYDROXYLATION OF THE AMINO-DEOXY-CONDURITOL-C RING-SYSTEM - A FORMAL SYNTHESIS OF THE AMINOCYCLITOL MOIETY OFTHE ANTIBIOTIC HYGROMYCIN-A

Authors
ARJONA O DEDIOS A PLUMET J SAEZ B
Citation
O. Arjona et al., HIGHLY DIASTEREOSELECTIVE BIS-HYDROXYLATION OF THE AMINO-DEOXY-CONDURITOL-C RING-SYSTEM - A FORMAL SYNTHESIS OF THE AMINOCYCLITOL MOIETY OFTHE ANTIBIOTIC HYGROMYCIN-A, Tetrahedron letters, 36(8), 1995, pp. 1319-1320
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
8
Year of publication
1995
Pages
1319 - 1320
Database
ISI
SICI code
0040-4039(1995)36:8<1319:HDBOTA>2.0.ZU;2-8
Abstract
A formal synthesis of the aminocyclitol fragment of the antibiotic Hyg romycin A is reported using, as a key step, a highly diastereoselectiv e bis-hydroxylation of an amino-deoxy-conduritol C derivative, easily accesible from an 7-oxanorbornenic derivative which in turn can be syn thesised from furan.