MULTIPLE ISOFORMS OF PISUM TRYPSIN-INHIBITORS RESULT FROM MODIFICATION OF 2 PRIMARY GENE-PRODUCTS

Authors
DOMONEY C WELHAM T SIDEBOTTOM C FIRMIN JL
Citation
C. Domoney et al., MULTIPLE ISOFORMS OF PISUM TRYPSIN-INHIBITORS RESULT FROM MODIFICATION OF 2 PRIMARY GENE-PRODUCTS, FEBS letters, 360(1), 1995, pp. 15-20
Citations number
29
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
360
Issue
1
Year of publication
1995
Pages
15 - 20
Database
ISI
SICI code
0014-5793(1995)360:1<15:MIOPTR>2.0.ZU;2-3
Abstract
Characterization of Pisum (pea) seed trypsin inhibitors (TI) and their corresponding cDNAs indicates that the pea TI gene family contains tw o genes, The existence of multiple TI isoforms can be attributed to po st-translational modifications of primary gene products, Post-translat ional processing at the C-terminus during the desiccation stage of see d development results in the appearance of TI isoforms with increased affinity for the target enzyme, trypsin.