NITRIC-OXIDE PRODUCTION DOES NOT DIRECTLY INCREASE MACROPHAGE CANDIDACIDAL ACTIVITY

Authors
VAZQUEZTORRES A JONESCARSON J BALISH E
Citation
A. Vazqueztorres et al., NITRIC-OXIDE PRODUCTION DOES NOT DIRECTLY INCREASE MACROPHAGE CANDIDACIDAL ACTIVITY, Infection and immunity, 63(3), 1995, pp. 1142-1144
Citations number
15
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
63
Issue
3
Year of publication
1995
Pages
1142 - 1144
Database
ISI
SICI code
0019-9567(1995)63:3<1142:NPDNDI>2.0.ZU;2-0
Abstract
Some activated murine macrophages produced nitrite but were unable to kill Candida albicans. Furthermore, a nitric oxide (NO) generator inhi bited C. albicans growth but was not candidacidal. Our results suggest that NO is candidastatic and that NO is not directly involved but is associated with or induces other macrophage candidacidal mechanisms.