MICROBIAL-PRODUCTION OF (-TRANS-ISOCHORISMIC ACID())

Authors
SCHMIDT K LEISTNER E
Citation
K. Schmidt et E. Leistner, MICROBIAL-PRODUCTION OF (-TRANS-ISOCHORISMIC ACID()), Biotechnology and bioengineering, 45(4), 1995, pp. 285-291
Citations number
39
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology and bioengineering → ACNP
ISSN journal
00063592
Volume
45
Issue
4
Year of publication
1995
Pages
285 - 291
Database
ISI
SICI code
0006-3592(1995)45:4<285:MO(A>2.0.ZU;2-#
Abstract
Two methods are described for the preparation of enantiomerically pure (+)-trans-isochorismic acid, an important metabolite of the postchori smate pathway. Both methods can be employed to prepare isotopically la beled isochorismic acid. One of the two methods is suitable to prepare bulk quantities of isochorismic acid using a recombinant strain of Kl ebsiella pneumoniae 62-1. (C) 1995 John Wiley and Sons, Inc.