M. Bobbio et al., PROBABILISTIC JUDGMENT AND CLINICAL DECISION IN THE USE OF EXERCISE ELECTROCARDIOGRAM, American journal of noninvasive cardiology, 8(4), 1994, pp. 190-193
The aim of this study was to verify, in a clinical setting whether dec
isions to perform coronary angiography and to modify drug treatment ar
e influenced by cardiologists' perception of coronary artery disease p
robability. Cardiologists referring patients for exercise electrocardi
ograms, because of suspected coronary artery disease, were asked to es
timate the probability of coronary artery disease before and after the
test. After the test they had to judge whether to refer patients for
coronary angiography or to change the current therapy. Cardiologists a
ssigned a higher coronary artery disease probability to patients they
would refer for coronary angiography (87.5%; 95% confidence interval 8
1.8-93.2%) than to those they would not refer (6.1%; 95% confidence in
terval 5.0-7.2; p < 0.0001). They also assigned a higher probability o
f coronary artery disease when they decided to increase drug treatment
(44.8%; 95% confidence interval 33.3-56.3%) than when it was decided
to reduce treatment (17.4%; 95% confidence interval 3.5-31.3%; p < 0.0
001). In conclusion, there is a close relationship between cardiologis
ts' assessment of coronary artery disease probability and their diagno
stic and therapeutic decisions when interpreting the exercise electroc
ardiogram.