N. Langlois et al., REGIOSELECTIVE AND STEREOSELECTIVE CYCLOA DDITIONS OF NITRONES AND ALPHA,BETA-UNSATURATED GAMMA-LACTAMS, Comptes rendus de l'Academie des sciences. Serie II. Mecanique, physique, chimie, astronomie, 320(3), 1995, pp. 155-158
alpha, beta-Unsaturated gamma-lactams 2 and 3 undergo regio- and stere
oselective 1,3-dipolar cycloadditions with N-benzyl- and N-methyl nitr
ones and can act as acceptors in conjugate addition of N-methylhydroxy
lamine. These reactions give access to highly functionalized pyrrolido
nes.