Anxiety occurs frequently in patients who are medically ill. A proper
search for the underlying cause of the anxiety is essential if the cli
nician is to make a correct diagnosis and initiate appropriate treatme
nt. Two aspects of the patient's history are particularly important du
ring assessment: the duration and severity of medical illness (and tre
atments) and the duration and severity of anxiety symptoms. When acute
anxiety is encountered, the clinician must rule out a rapidly worseni
ng medical condition, substance-induced anxiety (toxicity or withdrawa
l), and a psychological reaction to stressors associated with the medi
cal illness. During evaluation of medically ill individuals with chron
ic anxiety, the clinician must rule out medical disorders that can mim
ic anxiety disorders, psychiatric disorders associated with anxiety sy
mptoms, and poor adjustment to the medical illness. it is also worth r
emembering that anxiety disorders occur at an increased frequency in i
ndividuals who have chronic medical illness.