This article examines the rates of detection for major depression and
other depressive disorders by family physicians as well as the differe
nces between detected and undetected cases in terms of a variety of de
mographic and clinical variables. A total of 1,580 family practice pat
ients completed a screening form and were rated by their physician. Pa
tients with elevated Center for Epidemiologic Studies-Depression Scale
(CES-D) scores were oversampled for possible interviews using the Str
uctured Clinical Interview for DSM-III-R (SCID). In the resulting weig
hted sample, family physicians detected 34.9% of cases of major depres
sion and 27.9% of cases of any depressive disorder. Detection was asso
ciated with pharmacological and psychological intervention. However, t
he undetected cases tended to be mildly depressed and higher functioni
ng. Presence of a current anxiety disorder facilitated detection. Over
all, the mildness of undetected depression and associated impairment h
ave implications for estimates of the consequences of primary care phy
sicians' low rates of nondetection and for the development of interven
tional strategies to improve their performance.