M. Michalon et al., EFFECTS OF LIGHT THERAPY ON NEUROPSYCHOLOGICAL FUNCTION AND MOOD IN SEASONAL AFFECTIVE-DISORDER, Journal of psychiatry & neuroscience, 22(1), 1997, pp. 19-28
To date, little attention has been paid to changes in neuropsychologic
al function in seasonal affective disorders (SAD), In this study, we i
nvestigated the performance of 30 patients with SAD on a wide range of
cognitive variables before and after 2 weeks of light treatment with
either white or placebo red light, as well as later in the summertime,
Performance of subjects with SAD on neuropsychological tests was comp
ared with a group of 29 age- and education-matched healthy control sub
jects. The most consistent deficits associated with SAD were on tests
of cognitive failures, visual memory, and visual-construction skills,
In contrast to specific bright light effects on psychiatric measures,
reports of cognitive failures did not change with either light treatme
nt, Visual memory and constructional deficits responded nonspecificall
y to treatment with either white or the presumed placebo red light, Su
rprisingly, visual memory deficits were seen again in the summer, at a
time when mood, cognitive failures, and other cognitive functions app
eared at normal levels, These data suggest that cognitive functioning
is affected by SAD, In addition, light treatment may have differential
effects on mood and cognition.