OMEGA-HYDRO-PERFLUOROALKYL PYRIMIDINYL NITROXIDES

Twenty-two polysubstituted 2-aminopyrimidines dissolved in F113 (CClF2 -CCl2F) solutions containing {[H(CF2CF2)(n)CO2](2), n = 1,2} and H(CF2 CF2)(n)NO [<----> H(CF2CF2)n(.) + NO] have been oxidized into detectab le omega-H-perfluoroalkyl pyrimidinyl nitroxides along with neutral pr oducts. A mechanism involving H-abstraction from the amino groups by H (CF2CF2)(n)N(O-.)(CF2CF2)(n)H and the subsequent radical steps was sug gested for the generation of the nitroxides. Some relationships betwee n a(N) values and the nature of the ring substituents are discussed.