We consider the effects of the time dependence of couplings due to the
ir dependence on a dilaton field, as occurs in superstring theory, as
well as in gravity theories of the Jordan-Brans-Dicke type. Because th
e scale parameters of couplings set by dimensional transmutation depen
d exponentially on the dilaton vev, we may obtain stringent limits on
the shift of the dilaton from the requirement that the induced shift i
n the couplings not vitiate the successful calculations of element abu
ndances for big-bang nucleosynthesis. These limits can be substantiall
y stronger than those obtained directly from the dilaton-induced chang
e in the gravitational coupling.