A 50-year-old male patient suffering from renal failure was maintained
in a stable condition by means of dialysis for 6 years. Hyperkeratoti
c papules appeared on his extremities. Histological investigation conf
irmed the diagnosis of perforating collagen disease. The dermatoses th
at are characterized by transepithelial elimination and associated wit
h renal failure are discussed. The authors consider that the acquired
perforating dermatoses should be regarded as a single entity.