H. Stracke et al., EFFECT OF THE ALDOSE REDUCTASE INHIBITOR ZOPOLRESTAT ON PERIPHERAL-NERVE CONDUCTION-VELOCITY IN THE STREPTOZOTOCIN-DIABETIC RAT, Perfusion, 8(1), 1995, pp. 16-19
In this pilot experiment to study the effects of CP-73,850 on MNCV in
diabetic rats, there was a suggestion that CP-73,850 could prevent the
deterioration in MNCV. Less animals died after STZ in the CP-73,850 t
reatment group. However, problems in the imbalance between groups at b
aseline meant that this observation cannot be supported by rigorous st
atistical analysis.