THE EXPRESSION OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) MESSENGER-RNA IN RAT-BRAIN - POSSIBLE ROLE OF ENDOGENOUS PACAPIN VASOPRESSIN RELEASE

Authors
MURASE T KONDO K ARIMA H IWASAKI Y ITO M MIURA Y OISO Y
Citation
T. Murase et al., THE EXPRESSION OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) MESSENGER-RNA IN RAT-BRAIN - POSSIBLE ROLE OF ENDOGENOUS PACAPIN VASOPRESSIN RELEASE, Neuroscience letters, 185(2), 1995, pp. 103-106
Citations number
20
Categorie Soggetti
Neurosciences
Journal title
Neuroscience letters → ACNP
ISSN journal
03043940
Volume
185
Issue
2
Year of publication
1995
Pages
103 - 106
Database
ISI
SICI code
0304-3940(1995)185:2<103:TEOPAC>2.0.ZU;2-Q
Abstract
We investigated the expression of pituitary adenylate cyclase-activati ng polypeptide (PACAP) mRNA in rat brain by in situ hybridization. PAC AP mRNA was prominently expressed in arcuate nucleus (ARC). Three days of water deprivation significantly increased plasma arginine vasopres sin and markedly potentiated the expression of PACAP mRNA in ARC. Thes e results suggest that PACAP in ARC may play some physiological role, possibly one of which may be the control of vasopressin